Composition: . each vial contains: doxorubicin hydrochloride…10mg lactose ……q. S.
Mechanism of action: Doxorubicin damages dna by intercalation of the anthracycline portion, metal ion chelation, or by generation of free radicals. Doxorubicin has also been shown to inhibit dna topoisomerase ii that is critical to dna function. Cytotoxic activity is cell cycle phase-nonspecific.