each ml contains fluorouracil 50mg (as flouracil sodium) water fro injectionq. S.
- flocil inj 250 mg/5ml
- flocil inj 500 mg /10ml
mechanism of action
as a pyrimidine analogue, it is transformed inside the cell into different cytotoxic metabolites which are then incorporated into dna and rna, finally inducing cell cycle arrest and apoptosis by inhibiting the cell's ability to synthesize dna. It is an s-phase specific drug and only active during certain cell cycles.
- colorectal cancer-adjuvant setting and advanced disease.
- breast cancer-adjuvant setting and advanced disease.
- gi malignancies, including anal, esophageal, gastric, and pancreatic cancer.
- head and neck cancer.
- topical use in basal cell cancer of skin and actinic keratoses.
- ovarian cancer.
protect from light. It should be stored at temperature 10o c- 30 o c
Ivipime 500mg (Combipack)
Ivipime 500mg (combipack).